Mycobacterial CYP121 as a target for anti-TB drug discovery
نویسندگان
چکیده
Despite the introduction of the first line treatment regimen forty years ago and the continuous trials since that time to introduce new regimens, tuberculosis (TB) is considered to be the cause of considerable mortality worldwide. Recent research highlighted the Mycobacterium tuberculosis (Mtb)CYP450s as potential drug targets. This article reviews mycobacterial CYP121 as a target for anti-TB drug discovery.
منابع مشابه
BioPhytMol: a drug discovery community resource on anti-mycobacterial phytomolecules and plant extracts
BACKGROUND Tuberculosis (TB) is the second leading cause of death from a single infectious organism, demanding attention towards discovery of novel anti-tubercular compounds. Natural products or their derivatives have provided more than 50% of all existing drugs, offering a chemically diverse space for discovery of novel drugs. DESCRIPTION BioPhytMol has been designed to systematically curate...
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